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Non-Human/In-Vitro Studies: Toxicity (Definition) Jump to: 2003: January  |  February  |  March  |  April  |   May  |   June  |   July  |   2002: January  |  February  |  March  |  April  |  May  |  June  |  July  |  August  |  September  |  October  |  November  |  December   2001: October  |  November  |  December July 2003 No updates available for July 2003 < June 2003 Setola V, Hufeisen SJ, Grande-Allen KJ, Vesely I, Glennon RA, Blough B, Rothman RB, Roth BL (2003) 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") Induces Fenfluramine-Like Proliferative Actions on Human Cardiac Valvular Interstitial Cells in Vitro. Mol Pharmacol 63: 1223-1229. May 2003 No updates available for May 2003 April 2003 Peng W, Simantov R (2003) Altered gene expression in frontal cortex and midbrain of 3,4- methylenedioxymethamphetamine (MDMA) treated mice: Differential regulation of GABA transporter subtypes. J Neurosci Res 72: 250-258. March 2003 No updates available for March 2003 February 2003 Fantegrossi WE, Godlewski T, Karabenick RL, Stephens JM, Ullrich T, Rice KC, Woods JH (2003) Pharmacological characterization of the effects of 3,4- methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice. Psychopharmacology 1:1 January 2003 No updates available for January 2003 December 2002 No updates available for December 2002 November 2002 Carvalho M, Hawksworth G, Milhazes N, Borges F, Monks TJ, Fernandes E, Carvalho F, Bastos ML (2002) Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells. Arch Toxicol 76: 581-588 Montiel-Duarte C, Varela-Rey M, Oses-Prieto J, Lopez-Zabalza M, Beitia G, Cenarruzabeitia E, Iraburu M (2002) 3,4-Methylenedioxymethamphetamine ("Ecstasy") induces apoptosis of cultured rat liver cells. Biochim Biophys Acta 1588: 26-32. October 2002 No updates available for October 2002 September 2002 Badon LA, Hicks A, Lord K, Ogden BA, Meleg-Smith S, Varner KJ (2002). Changes in Cardiovascular Responsiveness and Cardiotoxicity Elicited during Binge Administration of Ecstasy. J Pharmacol Exp Ther 302: 898-907. Gesi M, Soldani P, Lenzi P, Ferrucci M, Giusiani A, Fornai F, Paparelli A (2002). Ecstasy during Loud Noise Exposure Induces Dramatic Ultrastructural Changes in the Heart. Pharmacol Toxicol 91: 29-33. August 2002 No updates available for August 2002 July 2002 No updates available for July 2002 June 2002 No updates available for June 2002 May 2002 Carvalho M, Carvalho F, Remiao F, de Lourdes Pereira M, Pires-Das-Neves R, de Lourdes Bastos M (2002). Effect of 3,4-methylenedioxymethamphetamine ("ecstasy") on body temperature and liver antioxidant status in mice: influence of ambient temperature. Arch Toxicol 76: 166-172 Gesi M, Lenzi P, Soldani P, Ferrucci M, Giusiani A, Fornai F, Paparelli A (2002). Morphological effects in the mouse myocardium after methylenedioxymethamphetamine administration combined with loud noise exposure. Anat Rec 267: 37-46 April 2002 Johnson EA, Shvedova AA, Kisin E, O'Callaghan JP, Kommineni C, Miller DB (2002). d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity. Brain Res 933: 150-163. March 2002 No updates available for March 2002 February 2002 No updates available for February 2002 January 2002 No updates available for January 2002 December 2001 Cannon DM, Keenan AK, Guiry PJ, Buon C, Baird AW, McBean GJ (2001). In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA. Br J Pharmacol 134: 1455-60. November 2001 No updates available for November 2001 October 2001 No updates available for October 2001