This is a very brief review and discussion of findings of MDMA-induced dopamine toxicity in squirrel monkeys and baboons reported by Ricaurte and colleagues (Ricuarte et al. 2002) that have since been retracted. The researchers retracted the findings on learning they had administered methamphetamine, and not MDMA, to their subjects. Though he fails to cite his sources, the author reports that Ecstasy use has increased from the 1980s, with people reporting more frequent use, and using greater numbers of tablets. It should be noted that MDMA content of Ecstasy pills has declined during the 1990s (Cole et al. 2003), potentially leading people to take more tablets per session in order to maintain a preferred dosage. Findings of an association between self-reported twitches and tremors and intensity of Ecstasy use gathered from an on-line study of Ecstasy users (Parrott et al. 2002) are presented as evidence supporting dopamine neurotoxicity in humans. Since Ricaurte and colleagues have since retracted their findings of dopaminergic toxicity, the significance of self-reported twitches and tremors in Ecstasy users remains unclear, though dystonias have been reported in stimulant users without any indication of their being associated with dopamine neurotoxicity.