This paper is a brief review intended to describe the history, effects and adverse events related to ecstasy use to an audience of people in the nursing community. Little attempt is made to locate primary research papers that might support any of the paper's claims except those concerning the potential neurotoxicity of MDMA, despite there being ample literature on ecstasy user demographics and drug effects. Instead, the authors relied heavily upon information provided by the National Institute on Drug Abuse (NIDA). The recommended treatment of adverse events are within the mainstream of medical recommendations, though previous reports have not suggested that opiates are commonly administered with ecstasy, nor do they recommend naloxone administration as a routine treatment for ecstasy-related visits to the emergency room. Errors exist throughout the paper. These include common errors about the history of MDMA, equating "entactogens" with "hallucinogenic amphetamines," equating tests of cognitive function with direct measures of serotonergic function and neglecting to address hyponatremia as a consequence of ecstasy use. The review does mention MDMA as an adjunct to psychotherapy, acknowledges the contentious nature of findings on potential neurotoxicity and notes that many adverse events are similar to those seen with stimulants. The overall impression of this paper is that it was written in haste, without any attempt to locate and reference research findings supportive of or opposing the authors' claims.
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