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Studies in Humans:
Studies of Ecstasy Users
(
Definition
)
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2001
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July 2003
No updates available for July 2003
June 2003
Curran HV, Verheyden SL (2003)
Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is highly correlated with human memory function.
Psychopharmacology 169: 91-103
Zhou JF, Zhou YH, Zhang L, Chen HH, Cai D (2003)
3,4-methylenedioxymethamphetamine (MDMA) abuse markedly inhibits acetylcholinesterase activity and induces severe oxidative damage and liperoxidative damage.
Biomed Environ Sci 16: 53-61.
May 2003
Daumann J, Fimm B, Willmes K, Thron A, Gouzoulis-Mayfrank E (2003)
Cerebral activation in abstinent ecstasy (MDMA) users during a working memory task: a functional magnetic resonance imaging (fMRI) study
. Cogn Brain Res 16: 479-87.
Zhou JF , Chen P, Zhou YH, Zhang L, Chen HH (2003)
3,4-Methylenedioxymethamphetamine (MDMA) Abuse may Cause Oxidative Stress and Potential Free Radical Damage
. Free Radical Research, 37 491-497
April 2003
Thomasius R, Petersen K, Buchert R, Andresen B, Zapletalova P, Wartberg L, Nebeling B, Schmoldt A (2003)
Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users
. Psychopharmacology 167: 85-96.
March 2003
Buchert R, Thomasius R, Nebeling B, Petersen K, Obrocki J, Jenicke L, Wilke F, Wartberg L, Zapletalova P, Clausen M (2003)
Long-term effects of "Ecstasy" use on serotonin transporters of the brain investigated by PET
. J Nucl Med 44: 375-84.
February 2003
No updates available for February 2003
January 2003
No updates available for January 2003
December 2002
Simon NG, Mattick RP (2002)
The impact of regular ecstasy use on memory function
. Addiction 97: 1523-1529.
November 2002
Gijsman HJ, Van Gerven JM, Verkes RJ, Schoemaker RC, Pieters MS, Pennings EJ, Hessing TJ, Cohen AF (2002)
Saccadic peak velocity and EEG as end-points for a serotonergic challenge test
. Hum Psychopharmacology 17: 83-89.
Parrott AC, Buchanan T, Scholey AB, Heffernan T, Ling J, Rodgers J (2002)
Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users
. Hum Psychopharmacology 17: 309-312.
October 2002
No updates available for October 2002
September 2002
Gerra G, Zaimovic A, Moi G, Giusti F, Gardini S, Delsignore R, Laviola G, Macchia T, Brambilla F (2002)
Effects of (+/-) 3,4-methylene-dioxymethamphetamine (ecstasy) on dopamine system function in humans
. Behav Brain Res 134: 403-410.
Lieb R, Schuetz CG, Pfister H, von Sydow K, Wittchen H (2002).
Mental disorders in ecstasy users: A prospective-longitudinal investigation
. Drug Alcohol Depend 68: 195-207.
Zakzanis KK, Young DA, Radkhoshnoud NF (2002)
Attentional processes in abstinent methylenedioxymethamphetamine (ecstasy) users
. Appl Neuropsychol 9: 84-91.
August 2002
Nixon PJ, Youngson CC, Beese A (2002)
Tooth surface loss: does recreational drug use contribute?
Clin Oral Investig 6: 128-30.
July 2002
Stuerenburg HJ, Petersen K, Baumer T, Rosenkranz M, Buhmann C, Thomasius R (2002).
Plasma concentrations of 5-HT, 5-HIAA, norepinephrine, epinephrine and dopamine in ecstasy users
. Neuroendocrinol Lett 23: 259-61.
June 2002
Fox, HC, McLean, A, Turner, JJD, Parrott, AC, Rogers R, Sahakian BJ (2002).
Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") polydrug users
. Psychopharmacology (Berl)., 162: 203-214
Obrocki J, Schmoldt A, Buchert R, Andresen B, Petersen K, Thomasius R (2002).
Specific neurotoxicity of chronic use of ecstasy
. Toxicol Lett 127: 285-97
May 2002
Gouzoulis-Mayfrank E, Becker S, Pelz S, Tuchtenhagen F, Daumann J (2002).
Neuroendocrine abnormalities in recreational ecstasy (MDMA) users: Is it ecstasy or cannabis?
Biological Psychiatry, 51, 766-769
Verheyden SL, Hadfield J, Calin T, Curran HV (2002).
Sub-acute effects of MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") on mood: evidence of gender differences
. Psychopharmacology (Berl), 161: 23-31
April 2002
No updates available for April 2002
March 2002
Reneman L, Majoie CB, Flick H, den Heeten GJ (2002).
Reduced N-acetylaspartate levels in the frontal cortex of 3,4- methylenedioxymethamphetamine (Ecstasy) users: preliminary results
. AJNR Am J Neuroradiol, 23: 231-237
Reneman L, Endert E, de Bruin K, Lavalaye J, Feenstra MG, de Wolff F, Booij J (2002).
The acute and chronic effects of MDMA ("Ecstasy") on cortical 5HT2A receptors in rat and human brain
. Neuropsychopharmacology, 26: 387-396
February 2002
Morgan, MJ, McFie, L, Fleetwood, LH and Robinson, JA (2002).
Ecstasy (MDMA): Are the psychological problems associated with its use reversed by prolonged abstinence?
Psychopharmacology (Berl), 159: 294-303
Reneman L, Booij, J, Lavalaye, J, de Bruin, K, Reitsma, JB, Boudewijn Gunning, W., den Heeten, GJ, van den Brink, W (2002).
Use of amphetamine by recreational users of ecstasy (MDMA) is associated with reduced striatal dopamine transporter densities: A [123I]-Beta-CIT SPECT study - preliminary report
. Psychopharmacology (Berl). 159: 335-340.
January 2002
Daumann J, Pelz S, Becker S, Tuchtenhagen F, Gouzoulis-Mayfrank E (2001).
Psychological profile of abstinent recreational Ecstasy (MDMA) users and significance of concomitant cannabis use
. Hum Psychopharmacol Clin Exp, 16:627-633
Dughiero G, Schifano F, Forza G (2001).
Personality dimensions and psychopathological profiles of Ecstasy users
. Hum Psychopharmacol Clin Exp, 16: 635-639
Fox HC, Toplis AS, Turner JJD, Parrott AC (2001).
Auditory verbal learning in drug-free polydrug users
. Human Psychopharmacol Clin Exp, 16: 613-618
Fox, HC, Parrott, AC and Turner, JJD (2001).
Ecstasy use; Cognitive deficits related to dosage rather than to self-reported problematic use of the drug
. J of Psychopharmacology, 15: 273-281
Gerra G, Zaimovic A, Ampollini R, Giusti F, Delsignore R, Raggi MA, Laviola G, Macchia T, Brambilla F (2001).
Experimentally induced aggressive behavior in subjects with 3,4- methylenedioxy-methamphetamine ("Ecstasy") use history: psychobiological correlates
. J Subst Abuse 13: 471-91
Heffernan TM, Jarvis H, Rodgers J, Scholey AB, Ling J (2001).
Prospective memory, everyday cognitive failure and central executive function in recreational users of Ecstasy
. Human Psychopharmacol, 16: 607-612
(Study 1)
Heffernan TM, Jarvis H, Rodgers J, Scholey AB, Ling J (2001).
Prospective memory, everyday cognitive failure and central executive function in recreational users of Ecstasy
. Human Psychopharmacol, 16: 607-612
(Study 2)
Heffernan TM, Jarvis H, Rodgers J, Scholey AB, Ling J (2001).
Prospective memory, everyday cognitive failure and central executive function in recreational users of Ecstasy
. Human Psychopharmacol, 16: 607-612
(Study 3)
Parrott AC, Milani RM, Parmar R, Turner JD (2001).
Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems
. Psychopharmacology (Berl) 159: 77-82.
Rodgers J, Buchanan T, Scholey AB, Heffernan TM, Ling J, Parrott A (2001).
Differential effects of ecstasy and cannabis on self-reports of memory ability; a web-based study
. Hum Psychopharmacol Clin Exp, 16: 619-625
December 2001
Reneman, L, Booij, J, de Bruin, K, Reitsma, JB, de Wolfe, FA, Gunning, WB, den Heeten, GJ, van den Brink, W (2001).
Effects of dose, sex and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons
. Lancet, 358: 1864-1869.
November 2001
Obergriesser, T, Ende, G, Braus, DF and Henn, FA (2001).
Hippocampal 1-HMRSI in ecstasy users
. European Archives of Psychiatry and Clinical Neuroscience, 251: 114-116.
Reneman, L, Lavalaye, J, Schmand, B, de Wolff, FA, van den Brink, W, den Heeten, GJ and Booij, J (2001).
Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy"): Preliminary findings.
Archives of General Psychiatry, 58: 901-906.
Reneman, L, Majoie, CBLM, Schmand, B, van den Brink, W and den Heeten, GJ (2001).
Pre-frontal N-acetylaspartate is strongly associated with memory performance in (abstinent) ecstasy users: Preliminary report.
Biological Psychiatry, 50: 550-554.
Zakzanis, KK and Young, DA (2001).
Executive function in abstinent MDMA ("ecstasy") users
. Medical Science Monitor, 7: 1292-1298.
October 2001
Croft, RJ, Klugman, A, Baldeweg, T and Gruzelier, JH (2001).
Electrophysiological evidence of serotonergic impairment in long-term MDMA ("ecstasy") users
. American Journal of Psychiatry, 158: 1687-1692