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Studies in Humans:
Clinical Trials
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November 2003
Tancer M and Johanson C-E (2003)
Reinforcing, subjective and physiological effects of MDMA in humans; A comparison with d-amphetamine and mCPP.
Drug and Alcohol Dependence 72: 33-44.
July 2003
No updates available for July 2003.
June 2003
No updates available for June 2003
May 2003
No updates available for May 2003
April 2003
No updates available for April 2003.
March 2003
Pizarro N, Llebaria A, Cano S, Joglar J, Farre M, Segura J, Torre Rd Rde L (2003)
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites by gas chromatography/mass spectrometry
. Rapid Commun Mass Spectrom 17: 330-336
February 2003
No updates available for February 2003
January 2003
No updates available for January 2003
December 2002
No updates available for December 2002
November 2002
No updates available for November 2002
October 2002
No updates available for October 2002
September 2002
Samyn N, De Boeck G, Wood M, Lamers C, De Waard D, Brookhuis K, Verstraete A, Riedel W (2002)
Plasma, oral fluid and sweat wipe ecstasy concentrations in controlled and real life conditions
. Forensic Sci Int 128: 90-97 (Study 1)
Samyn N, De Boeck G, Wood M, Lamers C, De Waard D, Brookhuis K, Verstraete A, Riedel W (2002)
Plasma, oral fluid and sweat wipe ecstasy concentrations in controlled and real life conditions
. Forensic Sci Int 128: 90-97 (Study 2)
August 2002
Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Palmi I, Ortuno J, Menoyo E, Segura J, de la Torre R (2002)
Cell-mediated immune response in MDMA users after repeated dose administration: studies in controlled versus noncontrolled settings
. Ann N Y Acad Sci 965: 421-433 (Study 1)
Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Palmi I, Ortuno J, Menoyo E, Segura J, de la Torre R (2002)
Cell-mediated immune response in MDMA users after repeated dose administration: studies in controlled versus noncontrolled settings
. Ann N Y Acad Sci 965: 421-433 (Study 2)
July 2002
Harris DS, Baggott M, Mendelson J, Mendelson JE, Jones RT (2002).
Subjective and hormonal effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans
. Psychopharmacology (Berl). 162: 396-405.
June 2002
No updates available for June 2002
May 2002
Pizarro N, Ortuno J, Farre M, Hernandez-Lopez C, Pujadas M, Llebaria A, Joglar J, Roset PN, Mas M, Segura J, Cami J, de la Torre R (2002).
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis
. J Anal Toxicol 26: 157-165.
April 2002
No updates available for April 2002
March 2002
Pichini S, Navarro M, Farre M, Ortuno J, Roset PN, Pacifici R, Zuccaro P, Segura J, de la Torre R (2002).
On-site testing of 3,4-methylenedioxymethamphetamine (ecstasy) in saliva with Drugwipe and Drugread: a controlled study in recreational users
. Clin Chem 48: 174-6.
February 2002
No updates available for February 2002
January 2002
Hernandez-Lopez C, Farre M, Roset PN, Menoyo E, Pizarro N, Ortuno J, Torrens M, Cami J, de La Torre R (2002).
3,4-Methylenedioxymethamphetamine (ecstasy) and alcohol interactions in humans: psychomotor performance, subjective effects, and pharmacokinetics
. J Pharmacol Exp Ther 300: 236-44.
December 2001
Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Ortuno J, Pujadas M, Bacosi A, Menoyo E, Segura J, de la Torre R (2001).
Effects of repeated doses of MDMA ("ecstasy") on cell-mediated immune response in humans
. Life Sci 69: 2931-41.
(Study 1)
Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Ortuno J, Pujadas M, Bacosi A, Menoyo E, Segura J, de la Torre R (2001).
Effects of repeated doses of MDMA ("ecstasy") on cell-mediated immune response in humans
. Life Sci 69: 2931-41.
(Study 2)
November 2001
Forsling, M, Fallon, JA, Kicman, AT, Hutt, AJ, Cowan, DA and Henry, JA (2001).
Arginine vasopressin release in response to the administration of 3,4- methylenedioxymethamphetamine ("ecstasy"): is metabolism a contributory factor?
Journal of Pharmacy and Pharmacology, 53: 1357-1363.
Tancer, ME and Johanson, C-E (2001).
The subjective effects of MDMA and mCPP in moderate MDMA users
. Drug and Alcohol Dependence, 65: 97-101.
October 2001
Frei, E, Gamma, A, Pascual-Marqui, R, Lehmann, D, Hell, D and Vollenweider, FX (2001).
Localization of MDMA-induced brain activity in healthy volunteers using low-resolution brain electromagnetic tomography (LORETA)
. Human Brain Mapping, 14: 152-165.
Navarro, M, Pichini, S, Farre, M, Ortuno, J, Roset, PN, Segura, J, de la Torre, R (2001).
Usefulness of saliva for measurement of 3,4-methylenedioxymethamphetamine and its metabolites: Correlation with plasma drug concentrations and effect of salivary pH
. Clinical Chemistry, 47: 1788-1795.
Segura, M, Ortuno, J, Farre, M, McLure, JA, Pujadas, M, Pizarro, N, Llebaria, A, Juglar, J, Roset, PN, Segura, J, and de la Torre, R (2001).
3,4-dihydroxymethamphetamine (HHMA): a major in-vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans
. Chemical Research in Toxicology, 14: 1203-1208.