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Research > MDMA-Assisted Psychotherapy
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MAPS is studying whether MDMA-assisted psychotherapy has the potential to heal the psychological and emotional damage caused by sexual assault, war, violent crime, and other traumas.
Our highest priority project is funding clinical trials of 3,4-methylenedioxymethamphetamine (MDMA) as a therapeutic tool to assist psychotherapy for the treatment of posttraumatic stress disorder (PTSD). Preliminary studies have shown that MDMA in conjunction with psychotherapy can help people overcome PTSD, and possibly other disorders as well. MDMA has "empathogenic" effects, meaning that it increases feelings of trust and compassion towards others.
MDMA is not the same as Ecstasy. Substances sold on the street under the name Ecstasy do often contain MDMA, but frequently also contain ketamine, caffeine, BZP, and other narcotics and stimulants. In laboratory studies, pure MDMA--but not Ecstasy--has been proven sufficiently safe for human consumption when taken a limited number of times in moderate doses.
MAPS is undertaking a 10 year, $10 million plan to make MDMA into an FDA-approved prescription medicine, and is currently the only organization in the world funding clinical trials of MDMA-assisted psychotherapy. For-profit pharmaceutical companies are not interested in developing MDMA into a medicine because the patent for MDMA has expired. Companies also cannot profit from MDMA because it is only administered a limited number of times, unlike most medications for mental illnesses which are taken on a daily basis.
See our prospectus outlining MAPS' MDMA/PTSD drug development plan.
View the timelines for each MAPS MDMA study.
See below for up-to-date information about MAPS' MDMA research, as well as information about the risks and benefits of MDMA use.
For media coverage of MAPS' MDMA research and other projects, see MAPS in the Media.
MDMA Research News Timeline
MDMA Research Timeline
MAPS-Sponsored Clinical Trials: MDMA-Assisted Psychotherapy for PTSD
MDMA/PTSD U.S. Study (Veterans of War)
MDMA/PTSD U.S. Flagship Study (Completed)
MDMA/PTSD U.S. Relapse Study
MDMA/PTSD U.S. Intern Study
MDMA/PTSD Australia Study
MDMA/PTSD Canada Study
MDMA/PTSD Israel Study
MDMA/PTSD Jordan Study
MDMA/PTSD Spain Study (Concluded)
MDMA/PTSD Switzerland Study
Training Protocol for MDMA/PTSD Researchers/Phase 1 Psychological Effects Study
MDMA for Cancer and End-of-Life Anxiety
MDMA-Assisted Psychotherapy in the Treatment of Anxiety Secondary to Advanced Stage Cancer
Auxiliary MAPS-Sponsored MDMA Projects
Treatment Manual for MDMA-Assisted Psychotherapy for Treatment of PTSD
Study of Psychological Defense Mechanisms During MDMA-Assisted Psychotherapy for Tx of PTSD
MDMA Literature, History, Testimonials, Risks
MAPS' MDMA Investigator's Brochure
MDMA Scientific Literature, Government Hearings, and Archive
Accounts of MDMA’s Healing Effects
Other MDMA Resources
Resources on the MAPS Site
Resources on Other Sites
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