Re: MAPS: FW: 2cb negative media reports

[Bob Wallace <bobw@xxxxxxxxxxx>]

Anthony Steele wrote:
>...The claims made for 2cb's negative effects are as follows:
>
>"At high doses (24mg), people experience extreme depersonalisation. >Intense hallucinations can cause irrational and dangerous behaviour, >especially if mixed with LSD or "speed" (amphetamines)

Well, any psychedelic can do this. 

>The danger of death by overdose is unlikely, although mixing nexus with
>other drugs could prove lethal. 

No evidence at all of anything like this (that I know of). No MAOI 
or P450 problems I know of. 

>Psychological damage caused by regular use may be irreversible."

True, for all psychedelics, for the small percentage of the population 
who is likely to become schizophrenic at some point. Generally a 
strong psychological stress is the final trigger. 

>Also, is there any possible neurotoxicity from 2CB, 

I asked this question of Sasha Shulgin and David Nichols at a seminar. 
They said no, from what they knew about the pharmacology of it and 
related drugs, neurotoxicity or other toxicity was very unlikely. 

>[LSD] is thought to precipitate latent mental illness - is there any >suggestion that 2cb can play the same role?

Sure, I think any psychedelic could do this. I would guess, at comparible 
doses, 2CB would be less likley to cause a psychotic break than LSD, 
as it affects peripheral perception somewhat more than inner cognition, 
compared with LSD/psilocybin/mescaline. 

>I am still somewhat fascinated by the idea that 2cb is banned because 
>of, not in spite of, it's relative harmlessness. If it was legal people would
>get used to the idea of recreational hallucinogens.

That's right, only the good-feeling and relatively safe plants and 
compounds get scheduled. All the delierant solanacaea (datura, 
jimson weed, mandrake, etc.) are dangerous and legal. 


- Bob Wallace (just my opinion);  bobw@xxxxxxxxxxx

Mind Books offers publications about psychedelics; 
books@xxxxxxxxxxx, or http://www.promind.com

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