maps • volume xv number 1 • Spring 2005
Ibogaine Outcome Study Report
By Valerie Mojeiko
The outcome study of people treated with ibogaine for chemical dependence has suffered several serious setbacks since my last report, as I've been racing to develop a research protocol and begin data collection at two precarious quasi-underground treatment facilities. With these setbacks, however, came several new possibilities, which, if led to fruition, will bring overall improvements to the original study.

During the early stages of protocol development, one of these facilities, the Iboga Therapy House in Vancouver, BC unexpectedly lost funding and was forced to shut down in August 2004. The clinic was previously funded entirely by marijuana seed entreprenuer Marc Emery, and provided treatments for free to those who qualified. Emery suffered some legal trouble last summer, in addition to a fire in the Marijuana Party Bookstore, two possible factors that led to his decision to abruptly withdraw funding for the facility.

On February 28, 2005, The Iboga Therapy House applied for a Canadian government grant to provide ibogaine detoxification services to 20 people as a pilot project.
The clinic had treated a total of 31 people, for whom preliminary data suggested positive outcomes. Our preliminary follow-up took place in June 2004. We were able to contact 20 out of about 31 people treated at the Iboga Therapy House, at varying lengths of time post-treatment. Our results suffer from a potential selection bias and should be considered tentative, short-term and involving subjects selected for treatment by the clinic for being most likely to succeed. Of the sample that we were able to contact, 6 out of 7 people who had been treated for cocaine or crack reported abstinence, 3 out of 8 people treated for opiates reported abstinence, and 4 out of 5 people treated for other substances or a combination of the above substances reported abstinence. Iboga Therapy House Program Director Sandra Karpetas and I presented these findings at the 16th annual International Transpersonal Psychology conference in Palo Alto, California.

After the loss of this clinic, we continued protocol development, intending to begin the study at the Ibogaine Association, a for-profit facility in Playas de Tijuana, Mexico offering low-cost treatments and busing in mostly American clients who fly into the San Diego airport.

In early January 2005, protocol development and training was finally finished. Data collection commenced on January 10, 2005 when two patients, one addicted to alcohol and one to crack cocaine, completed baseline interviews with Ibogaine Association Aftercare Coordinator Jill Stammer.

After gathering outcome data from the first three patients treated sequentially, the Mexican clinic unexpectedly shut down, causing the study to be halted prematurely. After spending nearly a year and a half developing a solid research protocol to collect and analyze outcome data from these two clinics, both had shut down.

When the Ibogaine Association closed its doors, MAPS turned once again to the Iboga Therapy House, and began offering assistance in applying for a grant to re-open the facility, and making plans for improvements to their program.

On February 28, 2005, The Iboga Therapy House applied for a Canadian government grant to provide ibogaine detoxification services to 20 people as a pilot project. The Drug Strategy Community Initiatives fund was created under the leadership of Health Canada in April 2004 to facilitate the development of local, provincial, territorial, national and community-based solutions to problematic substance use and to promote public awareness of problematic substance use.

Ibogaine-assisted therapy fills a gap in British Columbia's existing harm reduction and treatment services by offering a unique detoxification option to treatment resistant chemically-dependent persons, such as those who are resistant to substitution therapies, and to methadone patients seeking an immediate detoxification. British Columbia, where North America's first heroin prescription trial is in development and North America's only safe injection site is currently operating, has a harm reduction and health promotion outlook to substance use problems that offers a fertile ground for implementing North America's first above-ground ibogaine clinic.

In an effort to assist the Iboga Therapy House in providing optimum services, MAPS organized a consultation for its staff with San-Francisco-based certified Holotropic Breathwork practitioner Dr. John Freeman. Dr. Freeman, who recently completed medical school in Mexico with an emphasis on cardiac care, visited the potential site for the new clinic and offered consultation on medical practices. Based on feedback from Dr. Freeman and others, the Iboga Therapy House will implement new medical procedures upon re-opening including purchasing emergency medical equipment and hiring a Level III EMT to supervise patients while they are experiencing the acute effects of ibogaine. The facility is also looking into hiring a Canadian doctor to oversee its operations. These measures are necessary to increase the safety of chemically-dependent patients treated with ibogaine, as ibogaine has the potential to cause heart failure and death, especially in people who have pre-existing medical issues (as a result of their drug use or other factors).

This spring we will hear announcement of the grant award. Plans are in progress to re-open the Iboga Therapy House as a for-profit business this summer if the grant is not awarded. MAPS will provide guidance and funding for an evaluation component to the Iboga Therapy House's program, once treatments have begun. Outcome data from the first 20 patients treated will be gathered by Iboga Therapy House Evaluation Coordinator Leah Martin. As Principal Investigator for MAPS' ibogaine outcome study, I will evaluate and analyze this data, to provide feedback for their program and to use in a research paper investigating outcomes of ibogaine therapy in the treatment of chemical dependence. For up-to-date progress reports on this study and to download the research protocol, visit: www.maps.org/ibogaine. If you would like to donate funds to help pay for the completion of the study, please e−mail me.

The Drug Strategy Community Initiatives fund was created
under the leadership of Health Canada in April 2004 to
facilitate the development of . . . community-based solutions
to problematic substance use and to promote public
awareness of problematic substance use.
Summer 2009 Vol. 19, No. 2 MAPS Research Update 2009
Spring 2009 Vol. 19, No. 1 Special Edition: Psychedelics and Ecology
Winter 2008/09 Vol. 18, No. 3 MAPS 2008 Financial Report
Summer 2008 Vol. 18, No. 2 Phoenix Rising: A Review of MAPS Research
Spring 2008 Vol. 18, No. 1 Special Edition: Technology and Psychedelics
Winter 2007 Vol. 17, No. 3 MAPS 06-07 Fiscal Yearly Report
Autumn 2007 Vol. 17, No. 2 Special Edition: Psychedelics and Self-Discovery
Spring/Summer 2007 Vol. 17, No. 1 The Chrysalis Stage
Winter 2006-7 Vol. 16, No. 3 Low Maintenance/High Performance
Autumn 2006 Vol. 16, No. 2 Technologies of Healing
Spring 2006 Vol. 16, No. 1 MAPS' 20th Anniversary
Winter 2005 Vol. 15, No. 3 MAPS final year as a teenager
Summer 2005 Vol. 15, No. 2 Israel Conference: MDMA/PTSD Research
Spring 2005 Vol. 15, No. 1 Accelerating flow of work and time
Autumn 2004 Vol. 14, No. 2 Rites of Passage: Kids and Psychedelics
Summer 2004 Vol. 14, No. 1 10 stamps and $250,000
Winter 2003 Vol. 13, No. 2 Holy Fire
Spring 2003 Vol. 13, No. 1 60th Anniversary of the Discovery of LSD
Autumn 2002 Vol. 12, No. 3 Vision
Summer 2002 Vol. 12, No. 2 "From celebration to frustration, and back again."
Spring 2002 Vol. 12, No. 1 Sex, Spirit & Psychedelics 2002
Autumn 2001 Vol. 11, No. 2 "In the future, it will be called Despair."
Spring 2001 Vol. 11, No. 1 "A Tidal Wave of Ecstasy!"
Autumn 2000 Vol. 10, No. 3 Creativity 2000
Summer 2000 Vol. 10, No. 2 Endings and Beginnings
Spring 2000 Vol. 10, No. 1 Making History in Slow Motion
Winter 1999/00 Vol. 9, No. 4 To the Ends of the Earth for MDMA Research...
Autumn 1999 Vol. 9, No. 3 MAPS' long-standing efforts to conduct...
Summer 1999 Vol. 9, No. 2 MAPS has come full circle...
Spring 1999 Vol. 9, No. 1 Patience, persistence and passion
Winter 1998/99 Vol. 8, No. 4 One of special pleasures of directing MAPS...
Autumn 1998 Vol. 8, No. 3 The Ayahuasca Issue (with Hofmann interview)
Summer 1998 Vol. 8, No. 2 Emotionally Powerful Anecdotes...
Spring 1998 Vol. 8, No. 1 Death Has a Way of Focusing One's Attention
Autumn 1997 Vol. 7, No. 4 Celebration is in Order
Summer 1997 Vol. 7, No. 3 Time Horizons
Spring 1997 Vol. 7, No. 2 Synchronicity
Winter 1996/97 Vol. 7, No. 1 Learning to Crawl
Autumn 1996 Vol. 6, No. 4 An Invitation for Dialogue
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New Year 1996 Vol. 6, No. 2 Sending Down Roots
Autumn 1995 Vol. 6, No. 1 Baby Steps
Summer 1995 Vol. 5, No. 4 Opportunity Amidst Obstacles
Winter 1994/95 Vol. 5, No. 3 Clinical Trials and Tribulations
Autumn 1994 Vol. 5, No. 2 Building Towards Clinical Trials
Summer 1994 Vol. 5, No. 1 Politics and Protocols: In Search of a Balance
Spring 1994 Vol. 4, No. 4 Laying the Groundwork
Winter 1993/94 Vol. 4, No. 3 A Time of Tests
Summer 1993 Vol. 4, No. 2 So Close Yet So Far
Spring 1993 Vol. 4, No. 1 Remembrance and Renewal
Winter 1992/93 Vol. 3, No. 4 Forging New Alliances
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Spring 1992 Vol. 3, No. 2 Small Steps, Gradual Progress, New Opportunities
Winter 1991/92 Vol. 3, No. 1 The Rekindling of a Thousand Points of Light
Summer 1991 Vol. 2, No. 2 MDMA protocol development with cancer patients
Winter 1990/91 Vol. 2, No. 1 MAPS' Swiss pharmacologically-assisted psychotherapy conference
Autumn 1990 Vol. 1, No. 3 What and Who is MAPS?
Summer 1989 Vol. 1, No. 2 Switzerland Leads the Way
Summer 1988 Vol. 1, No. 1 MDMA can become a legal medicine